HitGen Unveils OpenDEL™ 5.0, Ushering in a New Era for Drug Discovery Research
Shanghai, China – August 27, 2025 – HitGen Inc., a leading biotechnology company dedicated to advancing drug discovery technologies, today announced the official launch of its groundbreaking OpenDEL™ 5.0 platform. This significant evolution of their proprietary DNA Encoded Library (DEL) technology promises to further accelerate and enhance the capabilities of research laboratories worldwide, particularly in the critical early stages of drug discovery.
The introduction of OpenDEL™ 5.0 represents a substantial leap forward in HitGen’s commitment to providing innovative and powerful tools for the scientific community. Building upon the established strengths of their DEL platform, this latest iteration boasts a range of enhancements designed to streamline the discovery process, broaden the scope of achievable research, and ultimately, facilitate the identification of novel therapeutic candidates.
At its core, HitGen’s DEL technology is renowned for its ability to generate massive, diverse chemical libraries where each small molecule is tagged with a unique DNA sequence. This DNA tag acts as a precise identifier, allowing for the rapid and efficient screening of millions, and even billions, of compounds simultaneously. OpenDEL™ 5.0 amplifies these capabilities, offering researchers unprecedented access to a more sophisticated and versatile platform.
Key advancements within OpenDEL™ 5.0 are expected to include:
- Expanded Library Diversity: The platform will feature an even greater chemical space accessible through an expanded range of building blocks and novel synthesis strategies. This allows for the exploration of a wider array of molecular architectures, increasing the likelihood of identifying unique and potent hits.
- Enhanced Screening Throughput and Efficiency: OpenDEL™ 5.0 is engineered for improved performance in screening assays, enabling researchers to process larger numbers of compounds with greater speed and precision. This translates to faster identification of promising leads and a more efficient use of valuable research resources.
- Streamlined Data Analysis and Integration: The platform is anticipated to incorporate advanced bioinformatics tools and user-friendly interfaces, facilitating seamless data analysis and interpretation. This will empower researchers to gain deeper insights from their screening experiments and accelerate the iterative process of drug optimization.
- Increased Flexibility and Customization: Recognizing the diverse needs of the research landscape, OpenDEL™ 5.0 is designed to offer greater flexibility, allowing laboratories to tailor screening strategies and library compositions to their specific project requirements and target modalities.
Dr. Li Jin, Chief Scientific Officer at HitGen, commented on the launch, stating, “We are thrilled to introduce OpenDEL™ 5.0 to the global research community. Our DEL technology has already proven its value in accelerating drug discovery, and with OpenDEL™ 5.0, we are providing an even more powerful and versatile engine for innovation. We believe this platform will empower researchers to tackle increasingly complex biological targets and bring life-changing therapies to patients faster than ever before.”
The introduction of OpenDEL™ 5.0 underscores HitGen’s dedication to pushing the boundaries of drug discovery technology. By providing access to such advanced platforms, HitGen aims to foster a collaborative environment where scientific breakthroughs can be achieved more readily. This latest development is set to be a significant asset for academic institutions, pharmaceutical companies, and biotechnology firms engaged in the pursuit of novel therapeutics for a wide range of diseases.
Advancing DEL Technology for the Research Lab: HitGen Introduces OpenDEL™ 5.0
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