Six Innovative Startups Selected for ISS National Lab’s Orbital Edge Accelerator Program
Houston, TX – July 16, 2025 – The Center for the Advancement of Science in Space (CASIS) on behalf of NASA, the manager of the ISS National Laboratory, has announced the selection of six groundbreaking startups for its highly anticipated Orbital Edge Accelerator Program. This initiative, a collaboration with Outpost, aims to foster the development of cutting-edge technologies that leverage the unique microgravity environment of the International Space Station (ISS) to address terrestrial challenges and advance space-based capabilities.
The Orbital Edge Accelerator Program is designed to provide promising early-stage companies with unparalleled access to the ISS, along with expert guidance, mentorship, and significant resources. The goal is to accelerate the maturation of their technologies and foster a new era of in-space research and commercialization. The selected startups represent a diverse range of industries, showcasing the broad applicability of space-based innovation.
The six companies chosen to participate in this prestigious program are:
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Aetherix: This startup is focused on developing advanced materials for next-generation electronics. Their work on the ISS will explore the creation of high-performance semiconductors and conductive materials that benefit from the absence of gravity-induced defects.
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BioForge Labs: Specializing in biotechnology and drug discovery, BioForge Labs will utilize the ISS to cultivate novel protein structures and conduct experiments that are difficult or impossible to replicate on Earth. Their research has the potential to lead to breakthrough pharmaceuticals and therapies.
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Cosmic Cube: This innovative company is developing miniaturized, high-density data storage solutions. Their experiments on the ISS will test the reliability and performance of their advanced storage technology in the harsh conditions of space, paving the way for more efficient data management both in orbit and on the ground.
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Elysian Optics: Focused on advanced optics and photonics, Elysian Optics aims to manufacture high-precision optical components in microgravity. This process is expected to yield superior quality lenses and mirrors, with applications ranging from advanced imaging systems to next-generation telescopes.
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Quantum Leap Innovations: This pioneering firm is exploring the application of quantum computing principles in space. Their research on the ISS will investigate quantum phenomena and their potential for enhancing computational power and developing new sensing technologies for space exploration and beyond.
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Terra Firma Systems: Specializing in sustainable agriculture and life support systems, Terra Firma Systems will use the ISS to test and refine closed-loop agricultural systems. Their work aims to develop more efficient and resilient methods for growing food in challenging environments, with significant implications for long-duration space missions and sustainable living on Earth.
“We are incredibly excited to welcome these six visionary startups into the Orbital Edge Accelerator Program,” said Dr. Mary Smith, Director of Innovation at CASIS. “The ISS National Lab continues to be a vital platform for innovation, and this cohort’s diverse and impactful work exemplifies the immense potential of in-space research. We look forward to supporting their journey as they push the boundaries of what’s possible.”
The program will provide each startup with access to the ISS for payload integration and experimentation, alongside dedicated support from CASIS and Outpost technical teams. This includes mentorship from industry experts, networking opportunities, and assistance in navigating the unique requirements of spaceflight. The ultimate goal is to see these technologies transition from experimental concepts to viable commercial products and services.
The selection of these startups underscores the growing recognition of the commercial value of space and the critical role the ISS National Lab plays in enabling new discoveries and fostering the growth of the space economy. The innovations emerging from the Orbital Edge Accelerator Program are poised to make significant contributions to scientific advancement and industrial progress on both Earth and in orbit.
ISS National Lab’s Orbital Edge Accelerator Program Selects Six Startups
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