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Paroxysmal Dyskinesia

Paroxysmal dyskinesia is a rare neurological movement disorder characterized by sudden, brief, involuntary muscle contractions. These movements can range from mild twitches to violent flailing. They can affect any part of the body, but most commonly involve the limbs, trunk, and face.

Paroxysmal dyskinesia is often classified into two types:

  • Paroxysmal non-kinesigenic dyskinesia (PNKD): These episodes occur spontaneously, without any obvious trigger.
  • Paroxysmal kinesigenic dyskinesia (PKD): These episodes are triggered by specific movements, such as walking, running, or reaching.

The exact cause of paroxysmal dyskinesia is unknown, but it is thought to be related to a dysfunction in the brain’s basal ganglia, which are responsible for controlling movement.

Paroxysmal dyskinesia can be diagnosed based on a patient’s symptoms and a physical examination. In some cases, additional tests, such as an MRI or EEG, may be needed to rule out other conditions.

There is no cure for paroxysmal dyskinesia, but medications can be used to control the symptoms. These medications include muscle relaxants, anticonvulsants, and dopamine agonists. In some cases, surgery may be necessary to treat severe cases of paroxysmal dyskinesia.

The prognosis for paroxysmal dyskinesia varies depending on the severity of the symptoms. In some cases, the symptoms can be mild and only occur occasionally. In other cases, the symptoms can be severe and disabling.


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